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New Products
Endoglycosidases
Exoglycosidases
Sialic Acid Products
Purification Cartridges
LudgerTag Labeling kits
HPLC Columns
Glycan Standards
CarboSequencing
Deglycosylation kits
MS/MS Data Analysis Tools
 
 
 
New Products
 
  QA-Bio and its partners are continually developing new products
  to meet the needs of the biopharmaceutical manufacturing community.
 
 
Endoglycosidases
 
  Cleave intact glycans from glycoproteins.
  Highly stable enzymes in clean preparations- no glycerol, NaCl, or other additives.

 
 
Exoglycosidases
 
  Cleave specific terminal-monosacharides from glycans.
  Allows detailed analysis of glycan structure.

 
 
Sialic Acid Products
 
  Enzymes and kits for the analysis of sialic acid (neuraminic acids).

  Sialic Acids are most often found at the terminal position of glycans, and
  therefore are a likely point of contact for glycan-ligand interactions.

 
 
Purification Cartridges
 
  Cartridges bind glycans but allow contaminants to be washed through.
  Applications include cleanup of glycans after enzyme digestions and fluorescent labeling.
 
 
LudgerTag Labeling kits
 
  For fluorescent labeling of glycans with a free reducing terminus.

  Labeled glycans may be detected by mass spectrometry, high-sensitivity
  fluorescence detection or monitoring of UV-absorbance.

 View Labeling Procedure (PDF file)

 
 
HPLC Columns
 
  Each LudgerSep HPLC column is individually tested for packing efficiency and selectivity
  Columns are subsequently qualified using a panel of labeled glycans.
 
 
Glycan Standards
 
All QA-Bio glycan standards are qualified to be >90% pure as assessed by a combinantion of H-NMR and HPLC.

QA-Bio supplies both flourescently labeled and unlabeled glycans.

 
 
CarboSequencing
 
  Includes the enzymes, and buffers required to sequence ten isolated, N-linked oligosaccharides.
 
 
Deglycosylation kits
 
  Easy to use kits for deglycosylating proteins in both native & denataured conditions.
  One 3 hour incubation removes all N-linked & most O-linked glycans.
 
 
MS/MS Data Analysis Tools
 

SimGlycan™ is an innovative MS/MS data analysis tool. SimGlycan™ predicts the glycan structure, scores it and generates a list of probable glycans that closely match the your experimental MS profile saving you the time and the frustration of laborious work.